Program
Thursday, April 10th
Welcome | 08:45
Bone Marrow Course | 09:00-10:30
Chairs: Daniel Arber and Leonie Saft
- Roos Leguit (Utrecht, NL) - The spectrum of reactive and therapy related changes in the bone marrow
- Daniel Arber (Chicago, USA) - Diagnostic approach to B-cell lymphoproliferations in the bone marrow
- Mats Ehinger (Lund, SE) - Flow cytometry in bone marrow diagnostics
Coffee break
Bone Marrow Course | 11:00 - 13:00
Chairs: Sa Wang and Alexandar Tzankov
- Hans-Michael Kvasnicka (Wuppertal, DE) - MDS and MDS/MPN overlap
- Alexandar Tzankov (Basel, CH) - Patterns of progression in myeloid neoplasms
- Arturo Bonometti (Milan, IT) - Diagnostic approach to histiocytic neoplasms in the bone marrow
- Konnie Hebeda (Nijmegen, NL) - AI applications in bone marrow diagnostics
Lunch break
Topic 1 Histiocytic and dendritic cell neoplasms | 14:00-15:10
Chairs: Roos Leguit and Claudio Tripodo
- Keynote lecture by Jean-Francois Emile (Paris, FR): Histiocytoses: general concepts, principles of classification, molecular features, future developments, and future unified classifications
- Falko Fend (Tübingen, DE) Plasmacytoid dendritic cell neoplasms and differential diagnosis
Coffee break
Bone Marrow Workshop | 15:40-17:40
Chairs: Falko Fend and Karl Sotlar
- Introduction
- Dr. Gorana Gasljevic, Ljubljana, “Histiocytic sarcoma associated with mediastinal germ cell tumor” (case #1734)
- Dr. Roos Leguit, Utrecht, “MPN NOS/U with massive histiocytic proliferation and indolent systemic mastocytosis (SM-AHN)” (case #1741)
- Dr. Mariko Yabe, New York, NY “Histiocytic sarcoma evolving from CLL/SLL” (case #1752)
- Dr. Gabriela Gheorghe, Memphis, TN “ALK+ histiocytosis” (case #1778)
- Dr. Giorgio Croci, Milano, “Myeloid neoplasm with eosinophilia and ETV6::SYK rearrangement and cutaneous histiocytosis” (case #1737)
- Dr. Réka Mózes, Budapest, “Rare case of blastic plasmocytoid dendritic cell neoplasm with extensive bone marrow involvment” (case #1751)
- Dr. Yen-Chun Liu, Memphis, TN, “Blastic plasmacytoid dendritic cell neoplasm with MYB::PLEKHO1 fusion” (case #1756)
- Case summary
Welcome reception
Annual General Meeting (EBMWG members only)
Friday, April 11th
Topic 2 Myeloid neoplasms with unusual patterns of disease progression - Session 1 | 09:00 - 10:40
Chairs: Hans-Michael Kvasnicka and Attilio Orazi
- Keynote lecture by Alessandro M. Vannucchi (Florence, Italy) - Progress in our molecular understanding of MPN
- Robert Hasserjian (Boston, USA) - Patterns of Response and Progression in Treated Myeloid Neoplasms
- Andreas Reiter (Mannheim, DE) - Progression of myeloid neoplasms from a clinical perspective
Coffee break
Topic 2 Myeloid neoplasms with unusual patterns of disease progression - Session 1 | 11:00 - 12:10
Chairs: Hans-Michael Kvasnicka and Attilio Orazi
- Keynote lecture by Rebekka Schneider-Kramann (Aachen, DE) - The role of the bone marrow niche in myeloid neoplasms
- Christian Schürch (Tübingen, DE) - The Use of Spatial Omics in Hematopathology
Lunch break
Topic 2 Myeloid neoplasms with unusual patterns of disease progression - Session 2 | 13:00 - 14:00
Chairs: Leonie Saft and Falko Fend
- Keynote lecture by Attilio Orazi (El Paso, USA) - Bone marrow pathology in the classification of myeloid neoplasms: a personal perspective
Mastocytosis symposium | 14.00-15.00
Chair: Karl Sotlar and Peter Valent
- Peter Valent (Vienna, AT) - Mastocytosis – the clinical perspective
- Karl Sotlar (Salzburg, AT) - The spectrum of bone marrow manifestations in systemic mastocytosis
Coffee break
Bone Marrow Workshop Topic 2 | 15:30-17:30
Chairs: Sa Wang and Alexandar Tzankov
- Introduction
- Dr. Giorgio Alberto Croci, Milano, “A complex progression of polycythaemia vera” (case #1748)
- Dr. Marco Pizzi, Padova, “Myeloproliferative neoplasm with neutrophilic progression” (case #1759)
- Dr. Hanine Medani, London, “Unusual progression pattern in a myelodysplastic neoplasm” (case #1783)
- Dr. Philipp Lohneis, Lübeck, “Polycythaemia vera with CMML-like progression (and acquired KRAS mutation)” (case #1726)
- Dr. Alex Jenei, Budapest, “Chronic myelomonocytic leukemia progression to a composite myeloid sarcoma and indeterminate cell histiocytosis” (case # 1758)
- Dr. Konnie Hebeda, Nijmegen, “Chronic myeloid leukemia “progression” in primary myelofibrosis” (case #1763)
- Case summary
Reception by the City and State of Salzburg | 18:45-20:00
Social Dinner | 20:30-23:30
Saturday, April 12th
Topic 3 B-cell lymphoproliferations in the bone marrow without defining molecular features | 09:00-10:40
Chairs: Konnie Hebeda and Mats Ehinger
- Keynote lecture by Davide Rossi (Bellinzona, CH) - Molecular landscape of small B-cell lymphomas (without defining features)
- Alberto Zamo (Würzburg, DE) - Diagnostics of small B cell lymphomas in the bone marrow
- Alexander Egle (Salzburg, AT) - Indolent B-cell proliferations in the bone marrow – the clinical perspective
Coffee break
Topic 3 B-cell lymphoproliferations in the bone marrow without defining molecular features | 11:00-12:00
Chairs: Konnie Hebeda and Mats Ehinger
- Sa Wang (Houston, USA) - Myeloid/lymphoid neoplasms with TK gene fusions – new entities
- Marco Herling (Leipzig, Germany) - Histiocytic and dendritic cell neoplasms - the clinical perspective
Lunch break
Bone Marrow Workshop Topic 3 | 13:00-15:00
Chairs: Gorana Gasljevic and Leonie Saft
- Introduction
- Dr Matsumoto, Pittsburgh, PA: “A case of B-cell lymphoma with IGH::CCND1 and BRAF V600 Mutation” (case #1745)
- Dr Soliman, Doha, Qatar: “Composite Lymphoma: Mantle cell lymphoma & small B-cell lymphoma with plasmacytic differentiation” (case #1754)
- Dr Vogelsberg, Tübingen: “Diagnostic Challenges in Splenic Diffuse Red Pulp Small B-cell lymphoma: A case with features overlapping with splenic marginal zone lymphoma” (case #1765)
- Dr Ehinger, Lund: “An unusual case of hairy cell leukemia without BRAF mutation” (case #1771)
- Dr Overkamp, Tübingen: “Diagnostic Challenges in Hairy-Cell Leukemia and its Variants: A Case with overlapping genetical and phenotypical features” (case #1780)
- Dr Alturkistani, Jeddah, Saudi Arabia: A “Rare case of splenic B-cell lymphoma” (case #1781)
- Case summary
Concluding remarks